Francisco Vega-Vazquez, M.D., Ph.D.
- Fax: 305-689-5899
- American Board of Pathology-Hematopathology
- American Board of Pathology-Anatomic
- Director of Hematopathology
- Professor of Pathology
My patient care activities center around the diagnosis of specimens obtained from patients being evaluated for leukemia or lymphoma. I interpret bone marrow core biopsy and aspirate specimens; lymph node and tissue biopsies; immunophenotypic analyses, including immunohistochemistry and flow cytometry; and peripheral blood smears.
The research in my laboratory is directed at exploring the role of Hedgehog signaling in the pathobiology of malignant lymphomas, in particular diffuse large B-cell lymphoma. We demonstrated that activation of Hedgehog signaling is involved in deregulated autonomous cell growth and survival of lymphoma cells. We are also investigating the role of stroma and Hedgehog signaling in inducing survival, proliferation and chemotolerance in malignant lymphomas. A global aim of our studies is to identify novel therapeutic targets in diffuse large B-cell lymphomas based on better understanding of the major oncogenic pathways deregulated in these neoplasms.
Complete List of Published Work in MyBibliography:http://www.ncbi.nlm.nih.gov/sites/myncbi/francisco.vega.1/bibliography/40772454/public/?sort=date&direction=descending
University of Navarra
Dr Vega is a renowned academic hematopathologist expertly qualified to consult in all areas of neoplastic hematopathology with an emphasis in lymph node pathology.